Targeting the "partners in crime".

نویسنده

  • Chris Pepper
چکیده

In this issue of Blood, Hertlein and colleagues present compelling in vitro and in vivo evidence that the novel HSP90 inhibitor 17-DMAG is a potent and selective killer of CLL cells that mediates its effects through the targeted inhibition of NF-B. Their findings describe a promising new therapeutic approach for the treatment of this disease.

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عنوان ژورنال:
  • Blood

دوره 116 1  شماره 

صفحات  -

تاریخ انتشار 2010